Payment & Shipping Terms:
|Category:||Drug Abuse TESGTING Kits||Format:||Strip A-PVP 4mm|
|Specimen:||Urine||Testing Time:||5 Minu|
|Shelf Life:||24 Months||Application:||A-PVP Abuse Test|
Drug Abuse Test Kit a-PVP (alpha-Pyrrolidinovalerophenone) Rapid Test 3mm strip , cut-off 1000ng/ml
a-PVP (alpha-Pyrrolidinovalerophenone) Rapid Diagnostic Test
alpha-Pyrrolidinovalerophenone (also known as α-PVP, A-PVP, alpha-PVP, and Flakka) is a synthetic stimulant substance of the cathinone and pyrrolidine chemical classes.1 α-PVP may be quantified in blood, plasma or urine to confirm a diagnosis of poisoning in hospitalized patients or to provide evidence in a medicolegal death investigation.2 It generally comes in the form of either a crystalline powder or crystallized shards which users can ingest to produce powerful but short-lived euphoric stimulant effects which are comparable to those of methamphetamine and cocaine when insufflated or vaporized. α-PVP has been reported to be the cause, or a significant contributory cause of death in suicides and overdoses caused by combinations of drugs.3, 4 It has also been linked to at least one death where it was combined with pentedrone and caused heart failure. The α-PVP Rapid Test Cassette (Urine) is a rapid urine screening test that can be performed without the use of an instrument. The test utilizes a monoclonal antibody to selectively detect elevated levels of alpha-Pyrrolidinovalerophenone in urine. The α-PVP Rapid Test Cassette (Urine) yields a positive result when alpha-Pyrrolidinovalerophenone in urine exceeds 1000ng/mL.
The α-PVP Rapid Test Cassette (Urine) is an immunoassay based on the principle of competitive binding. Drugs which may be present in the urine specimen compete against the drug conjugate for binding sites on the antibody. During testing, a urine specimen migrates upward by capillary action. alpha-Pyrrolidinovalerophenone, if present in the urine specimen below 1000ng/mL, will not saturate the binding sites of antibody-coated particles in the test. The antibody-coated particles will then be captured by immobilized alpha-Pyrrolidinovalerophenone conjugate and a visible colored line will show up in the test line region. The colored line will not form in the test line region if the alpha-Pyrrolidinovalerophenone level exceeds 1000ng/mL because it will saturate all the binding sites of anti-alpha-Pyrrolidinovalerophenone antibodies. A drug-positive urine specimen will not generate a colored line in the test line region because of drug competition, while a drug-negative urine specimen or a specimen containing a drug concentration lower than the cut-off will generate a line in the test line region. To serve as a procedural control, a colored line will always appear in the control line region, indicating that proper volume of specimen has been added and membrane wicking has occurred.
SPECIMEN COLLECTION AND STORAGE
The urine specimen must be collected in a clean and dry container. Urine collected at any time of the day may be used. Urine specimens exhibiting visible particles should be centrifuged, filtered, or allowed to settle to obtain clear specimen for testing. Specimen.
Urine specimens may be stored at 2-8°C for up to 48 hours prior to testing. For long-term storage, specimens may be frozen and stored below -20°C. Frozen specimens should be thawed and mixed before testing.
Store as packaged in the sealed pouch either at room temperature or refrigerated (2-30°C). The test is stable through the expiration date printed on the sealed pouch. The test must remain in the sealed pouch until use. DO NOT FREEZE. Do not use beyond the expiration date.
1. The 6-MAM Rapid Test Cassette provides only a qualitative, preliminary analytical result. A secondary analytical method must be used to obtain a confirmed result. Gas chromatography/mass spectrophotometry (GC/MS) is the preferred confirmatory method2.3.
2. It is possible that technical or procedural errors, as well as other interfering substances in the urine specimen may cause erroneous results.
3. Adulterants, such as bleach and/or alum, in urine specimens may produce erroneous results regardless of the analytical method used. If adulteration is suspected, the test should be repeated with another urine specimen.
4. A positive result indicates presence of the drug or its metabolites but does not indicate level of intoxication, administration route or concentration in urine.
5. A negative result may not necessarily indicate drug-free urine. Negative results can be obtained when drug is present but below the cut-off level of the test.
A side-by-side comparison was conducted using the alpha-PVP Rapid Test Cassette (Urine) and GC/MS. The following results were tabulated:
Table 1: Specimen Correlation
|Alpha-PVP Rapid Test||Results||Positive||Negative|
|ORIENT NEW LIFE MEDICAL CO., LTD.|
|Email:||Jerry @ newlifebiotest .com|
Contact Person: Jerry Meng